Our immune system has the task of protecting us against bacteria and viruses. Our bodies are also equipped to handle everyday stress–that is, stress that lasts only briefly.
On the other hand, a difficult, stressful situation or long-term increase in stress can negatively affect the immune system. This kind of long-term stress can develop when a close family member dies or when adults are caught in tough, unmanageable situations.
The research study shows that children in highly-stressed families had a high level of cortisol, which is a biological marker of stress. This supports the idea that the children were stressed. The research study also points towards the fact that a high level of stress negatively affects the immune system–that is, it is not as resistant when the body is exposed to a high level of stress. Instead, the immune system reacts to substances in the body that should be left alone, which perhaps is linked to an autoimmune reaction.
The study included families with five-year-old children (derived from the ABIS study). The parents answered questions regarding stress and prospective difficulties that had impacted the family, such as divorce or unemployment.
The answers led the researchers to identify a group of children who probably experienced high levels of stress in their families, and a group of children who presumably had grown up with normal stress levels.
The research group at the School of Health Sciences in Jönköping will work further on the project to understand more about how a high level of stress can affect the body. This time, the researchers will turn to young people in the 18-22 age group.
“These young people can themselves report negative experiences in their daily lives and also negative experiences during their childhood” says Maria Faresjö, professor at the School of Health Sciences, which will also lead the continued research project.
The article, “Psychological stress in children may alter the immune response”, is being published in Journal of Immunology (2014, DOI: 10.4049/jimmunol.1301713).
Maria Faresjö, professor of Biomedical Laboratory Science at the School of Health Sciences, Jönköping University, Sweden. e-mail: firstname.lastname@example.org; Cell phone: +46-70 979 7031
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