Early signs of Alzheimer’s detected in cerebrospinal fluid

These results demonstrate that in cases of Alzheimer‘s, inflammatory processes in the brain evolve dynamically and are precursors of dementia. These immune responses can be detected by means of a protein in the cerebrospinal fluid, offering physicians the possibility to trace the progression of the disease. The study results are published in the journal “Science Translational Medicine”.

Original Publication
„Early changes of CSF sTREM2 in Dominantly Inherited Alzheimer’s Disease follow markers of Amyloid Deposition and Neuronal Injury“, Marc Suárez-Calvet, Miguel Ángel Araque Caballero, Gernot Kleinberger, Randall J. Bateman, Anne M. Fagan, John C. Morris, Johannes Levin, Adrian Danek, Michael Ewers, Christian Haass, Science Translational Medicine, DOI: 10.1126/scitranslmed.aag1767

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